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Project 1

Project 1: Design and synthesis of fungicide nanodelivery systems for controlling Ganoderma disease in oil palm

Oil palm is one of important crops in Malaysia. However, fungus especially Ganoderma which cause basal stem rot (BSR) disease in oil palm devastates thousands of hectares of plantings. The economic loss caused by this pathogen is up to 500 million USD a year. Therefore, an effective method for the prevention and amelioration of BSR disease could save millions of dollars a year.
Nanoscience and nanotechnology have been proven to provide novel and improved solutions to many challenges currently faced by agriculture sector. Our previous works showed that agrochemicals such as plant growth regulator, phytohormone and pesticides could be intercalated into layered materials for the formation of nano-agrochemicals with controlled release properties. Therefore, we believed fungicides such as hexaconazole and dazomet could be also used as guests for the formation of fungicide nanodelivery systems with slow release properties which is important for prolonging the availability and efficacy of the fungicide.


Prof. Dr. Mohd Zobir bin Hussein
Institute of Advanced Technology (ITMA),
Universiti Putra Malaysia,
Serdang, Selangor, Malaysi

Novel controlled fungicide carrier for anti-fungus should have long circulation time, the ability to target fungus cells without affecting healthy cells, and eventually the ability to efficiently deliver and release fungicide into target site. Currently, fungicides such as hexaconazole and dazomet are being directly applied for this purpose.
Fungicide nanodelivery system (FUNADS) with controlled release capability is superior, as the concentration window of the fungicide can be maintained for a desired duration. This will decrease fungicide wastage and increase fungicide efficacy.


  • To design and synthesise novel fungicide nanodelivery system (FUNADS).
  • To characterise FUNADS and optimise the process parameters.
  • To study the toxicity and controlled release properties of FUNADS. d. Laboratory, nursery and field studies of FUNADS

Expected Outcome

A novel fungicide nanodelivery systems together with the in vitro and in vivo studies is hoped to uncovered


Dr. Idris Abu Seman
Head of Ganoderma and Diseases Research for Oil Palm Unit,
Ibu Pejabat MPOB, 6, Persiaran Institusi, Bandar Baru Bangi
Kajang, Selangor
 Assoc. Prof. Dr Sharida binti Fakurazi
Head of Laboratory of Vaccine and Immunotherapeutics,
Institute of Bioscience, Universiti Putra Malaysia (UPM),
Serdang, Selangor, Malaysia.
 Professor Datin Paduka Dr. Khatijah Yusoff
Dean of the Faculty of Biotechnology and Biomolecular Sciences,
Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia.
Prof. Dr. Rickey Yada
Department of Food Science, University of Guelph,
Guelph, Canada
 Prof Dr A. Perez-de-Luque,
CSIC, Institute for Sustainable Agriculture, Apartado 4084,
Cordoba, Spain.




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